| 2025-03-01 15:00:25March 1, 2025 |  Mamelodi Sundowns Ladies vs Royal AM Ladies  | 15:00:253:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-03-09 15:00:45March 9, 2025 | Mamelodi Sundowns Ladies vs JVW FC  | 2 - 0 | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-03-15 15:00:53March 15, 2025 |  University of JHB FC vs Mamelodi Sundowns Ladies | 15:00:533:00 pm | Hollywoodbets Super League | UJ Soweto soccer stadium |
| 2025-03-19 18:00:45March 19, 2025 |  University Of Pretoria vs Mamelodi Sundowns Ladies | 18:00:456:00 pm | Hollywoodbets Super League | ABSA TUKS Stadium |
| 2025-03-22 15:00:20March 22, 2025 | Mamelodi Sundowns Ladies vs UWC  | 15:00:203:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-03-29 15:00:40March 29, 2025 | Mamelodi Sundowns Ladies vs Durban Ladies FC  | 15:00:403:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-04-12 15:00:19April 12, 2025 |  University of Cape Town FC vs Mamelodi Sundowns Ladies | 15:00:193:00 pm | Hollywoodbets Super League | Kopano stadium |
| 2025-04-19 15:00:30April 19, 2025 | Mamelodi Sundowns Ladies vs Ezemvelo Women’s FC  | 15:00:303:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-04-26 15:00:56April 26, 2025 |  Copper Belts FC vs Mamelodi Sundowns Ladies | 15:00:563:00 pm | Hollywoodbets Super League | Seshego Stadium |
| 2025-04-30 15:00:19April 30, 2025 |  City Lads vs Mamelodi Sundowns Ladies | 15:00:193:00 pm | Hollywoodbets Super League | Isaac Wolfson Stadium |
| 2025-05-04 15:00:08May 4, 2025 | Mamelodi Sundowns Ladies vs University of Fort Hare  | 15:00:083:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-05-10 15:00:17May 10, 2025 |  First Touch Academy vs Mamelodi Sundowns Ladies | 15:00:173:00 pm | Hollywoodbets Super League | Peter Mokaba Stadium |
| 2025-05-17 15:00:34May 17, 2025 | Mamelodi Sundowns Ladies vs Richmond United  | 15:00:343:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-05-24 15:00:30May 24, 2025 |  TUT Football Club vs Mamelodi Sundowns Ladies | 15:00:303:00 pm | Hollywoodbets Super League | TUT Pretoria Stadium |
| 2025-05-31 15:00:09May 31, 2025 | Mamelodi Sundowns Ladies vs TS Galaxy Ladies  | 15:00:093:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-06-07 15:00:19June 7, 2025 | Royal AM Ladies vs Mamelodi Sundowns Ladies | 15:00:193:00 pm | Hollywoodbets Super League | Harry Gwala Stadium |
| 2025-06-14 15:00:33June 14, 2025 | JVW FC vs Mamelodi Sundowns Ladies | 15:00:333:00 pm | Hollywoodbets Super League | UJ Soweto soccer stadium |
| 2025-06-21 15:00:49June 21, 2025 | Mamelodi Sundowns Ladies vs University of JHB FC | 15:00:493:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-08-02 15:00:12August 2, 2025 | UWC vs Mamelodi Sundowns Ladies | 15:00:123:00 pm | Hollywoodbets Super League | University of Western Cape Stadium |
| 2025-08-06 15:00:15August 6, 2025 | Mamelodi Sundowns Ladies vs University Of Pretoria | 15:00:153:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-08-10 15:00:27August 10, 2025 | Durban Ladies FC vs Mamelodi Sundowns Ladies | 15:00:273:00 pm | Hollywoodbets Super League | King Zwelithini Stadium |
| 2025-08-16 15:00:29August 16, 2025 | Mamelodi Sundowns Ladies vs University of Cape Town FC | 15:00:293:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-08-23 15:00:30August 23, 2025 | Ezemvelo Women’s FC vs Mamelodi Sundowns Ladies | 15:00:303:00 pm | Hollywoodbets Super League | King Zwelithini Stadium |
| 2025-08-30 15:00:34August 30, 2025 | Mamelodi Sundowns Ladies vs Copper Belts FC | 15:00:343:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-09-06 15:00:31September 6, 2025 | Mamelodi Sundowns Ladies vs City Lads | 15:00:313:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-09-13 15:00:40September 13, 2025 | University of Fort Hare vs Mamelodi Sundowns Ladies | 15:00:403:00 pm | Hollywoodbets Super League | Davidson Stadium, Alice |
| 2025-09-20 15:00:58September 20, 2025 | Mamelodi Sundowns Ladies vs First Touch Academy | 15:00:583:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-09-24 15:00:00September 24, 2025 | Richmond United vs Mamelodi Sundowns Ladies | 15:00:003:00 pm | Hollywoodbets Super League | Merino Park Stadium, De Aar |
| 2025-09-28 15:00:28September 28, 2025 | Mamelodi Sundowns Ladies vs TUT Football Club | 15:00:283:00 pm | Hollywoodbets Super League | Lucas Moripe Stadium |
| 2025-10-05 15:00:41October 5, 2025 | TS Galaxy Ladies vs Mamelodi Sundowns Ladies | 15:00:413:00 pm | Hollywoodbets Super League | KaNyamazane Stadium |
